The novel coronavirus (COVID-19) pandemic is creating a humanitarian and economic crisis. Amid the chaos, though, lies a simple preventive practice: handwashing with soap. During times of crisis, we must remember that handwashing with soap is a powerful tool to combat infectious diseases like COVID-19, and it is crucial for us to sustain handwashing practices and innovations once the pandemic has ended. Private-sector engagement, especially through public-private partnerships like the Global Handwashing Partnership, can play a significant role in developing immediate and long-term infectious disease solutions.